Prevention of congenital abnormalities by periconceptional multivitamin supplementation.
نویسندگان
چکیده
منابع مشابه
Prevention of congenital abnormalities by periconceptional multivitamin supplementation.
OBJECTIVE To study the effect of periconceptional multivitamin supplementation on neural tube defects and other congenital abnormality entities. DESIGN Randomised controlled trial of supplementation with multivitamins and trace elements. SETTING Hungarian family planning programme. SUBJECTS 4156 pregnancies with known outcome and 3713 infants evaluated in the eighth month of life. INTER...
متن کاملPostnatal somatic and mental development after periconceptional multivitamin supplementation.
The effect of periconceptional multivitamin supplementation on postnatal development was studied in a randomised controlled trial comparing the use of a multivitamin tablet (Elevit Pronatal) with a tablet containing trace elements as part of the Hungarian Optimal Family Planning Programme. Of 4122 liveborn infants, 3356 were examined after the eighth month of life and medical records were obtai...
متن کاملApparent prevention of neural tube defects by periconceptional vitamin supplementation.
An earlier preliminary paper is expanded. Women who had given birth to one or more infants with a neural tube defect were recruited into a trial of per conceptional vitamin supplementation. Two hundred mothers attending five centres were fully supplemented (FS), 50 were partially supplemented (PS), and 300 were unsupplemented (US). Neural tube defect recurrences in the study pregnancies were 1 ...
متن کاملPericonceptional vitamin supplementation and the prevention of neural tube defects.
A comparison has been made of the effectiveness of periconceptional vitamin supplementation for the prevention of recurrence of neural tube defects (NTD) in south-east England and Northern Ireland. These areas represent the extremes of birth prevalence of NTD (low and high respectively) within the United Kingdom. Vitamin therapy resulted in a slightly less than two-fold reduction in the recurre...
متن کاملPrevention of Neural Tube Defects and proper folate periconceptional supplementation.
"Patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community." (WHO, 1985).The WHO statement on the rationale use of medicines, and the reasons why medicines are often used irrationally should be carefully considered even in the present days, as physicia...
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ژورنال
عنوان ژورنال: BMJ
سال: 1993
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.306.6893.1645